This extremely successful textbook emphasizes the fundamentals of medicinal chemistry with specific reference to drug design, drug synthesis, and drug action from a pharmaceutical organic chemical perspective. Thus, it really enables the reader to extend knowledge beyond what is known with regard to several known classes of drug molecules. Particular care has been taken to preserve the organization, presentation and rhythm of the fourth edition.
Medicinal Chemistry in its Fifth Revised and Expanded Edition presents Text: * A Medicinal Chemist`s perspective in knowing the skill how drugs are designed-synthesized to muster a definite better understanding of drug chemistry. * Includes thorough revision of chemical structures-emphasizing keywords, latest references, Selected Bibliography and Footnotes. * Incorporates generic names, trade names, official status, uses, doses, and mechanism of action. * Written in a lucid, informal, simple style in order that the undergraduates/postgraduates may easily grasp the basic ideas and concepts presented. * Two new Chapters viz. Pro-Drug Approach in Drug Design and Drug Discovery via Enzyme Inhibition have been included so as to facilitate the postgraduate students majoring in Pharmaceutical Chemistry courses in Indian Universities and abroad.
Table of Contents * Drug Design-A Rational Approach * Physical-Chemical Factors and Biological Activities * Molecular Modeling and Drug Design * General Anaesthetics * Local Anaesthetics * Sedatives and Hypnotics * Anticonvulsants * Muscle Relaxants * Central Nervous System Stimulants * Antipyretic Analgesics * Narcotic Analgesics (Opiate Analgesics) * Cardiovascular Drugs * Autonomic Drugs * Diuretics * Antihistamincs * Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) * Antiparkinsonism Agents * Expectorants and Antitussives * Sulphonamides * Antimalarials * Anthelmintics * Insulin and Oral Hypoglycemic Agents * Steroids * Adrenocortical Steroids * Antibiotics * Antimycobacterial Drugs * Antineoplastic Agents * Antipsychotics (Tranquilizers) * Antiviral Drugs * Newer Drugs for Newer Diseases * Pro-drug Approach in Drug Design * Drug Discovery via Enzyme Inhibition
Table of Contents * Drug Design-A Rational Approach * Physical-Chemical Factors and Biological Activities * Molecular Modeling and Drug Design * General Anaesthetics * Local Anaesthetics * Sedatives and Hypnotics * Anticonvulsants * Muscle Relaxants * Central Nervous System Stimulants * Antipyretic Analgesics * Narcotic Analgesics (Opiate Analgesics) * Cardiovascular Drugs * Autonomic Drugs * Diuretics * Antihistaminics * Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) * Antiparkinsonism Agents * Expectorants and Antitussives * Sulphonamides * Antimalarials * Anthelmintics * Insulin and Oral Hypoglycemic Agents * Steroids * Adrenocortical Steroids * Antibiotics * Antimycobacterial Drugs * Antineoplastic Agents * Antipsychotics (Tranquilizers) * Antiviral Drugs * Newer Drugs for Newer Diseases * Pro-drug Approach in Drug Design * Drug Discovery via Enzyme Inhibition
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